In vitro enzymatic degradation of poly (glycerol sebacate)-based materials.

@article{Liang2011InVE,
  title={In vitro enzymatic degradation of poly (glycerol sebacate)-based materials.},
  author={Shu-Ling Liang and Xue-yuan Yang and Xi-Ya Fang and Wayne D Cook and George A. Thouas and Q Z Chen},
  journal={Biomaterials},
  year={2011},
  volume={32 33},
  pages={8486-96}
}
Enzymatic degradation is a major feature of polyester implants in vivo. An in vitro experimental protocol that can simulate and predict the in vivo enzymatic degradation kinetics of implants is of importance not only to our understanding of the scientific issue, but also to the well-being of animals. In this study, we explored the enzymatic degradation of PGS-based materials in vitro, in tissue culture medium or a buffer solution at the pH optima and under static or cyclic mechanical-loading… CONTINUE READING

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