In vitro effects of the new calcium antagonist lacidipine.

@article{Kawada1993InVE,
  title={In vitro effects of the new calcium antagonist lacidipine.},
  author={T. Kawada and H. T. Sun and M. Nakazawa and S. Imai},
  journal={Japanese journal of pharmacology},
  year={1993},
  volume={62 3},
  pages={
          289-96
        }
}
The effects of lacidipine (LC), a new dihydropyridine calcium antagonist, were studied in comparison with those of nifedipine (NF) in isolated arteries of the dog (DG-AR) and isolated aorta (GP-AO), left and right atria (GP-LA, GP-RA) and ventricular papillary muscles (GP-PM) of the guinea pig. In DG-AR precontracted with high K+, LC and NF produced a concentration-dependent relaxation. The relaxant effect of LC was most potent in the basilar artery. The calcium antagonistic effects of LC was 8… Expand
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