In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity.

@article{Singh2015InVE,
  title={In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity.},
  author={R K Singh and Ramakrishna Rachumallu and Manisha Bhateria and Jagadeesh Panduri and Rabi Sankar Bhatta},
  journal={Xenobiotica; the fate of foreign compounds in biological systems},
  year={2015},
  volume={45 8},
  pages={
          741-9
        }
}
1. For centuries Bacopa monniera (BM) has been used as an herbal drug for the treatment of various mental ailments. A chemically standardized alcoholic extract of BM is clinically available over the counter herbal remedy for memory enhancement in children and adults. Consumption of herbal preparations has been reported to alter the function of membrane transporters, especially P-glycoprotein (P-gp), ATP-dependent drug efflux transporter responsible for the development of herb-drug interactions… CONTINUE READING
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