In vitro effects of platelet-rich gel supernatants on histology and chondrocyte apoptosis scores, hyaluronan release and gene expression of equine cartilage explants challenged with lipopolysaccharide

@article{Carmona2016InVE,
  title={In vitro effects of platelet-rich gel supernatants on histology and chondrocyte apoptosis scores, hyaluronan release and gene expression of equine cartilage explants challenged with lipopolysaccharide},
  author={J. Carmona and D. L. R{\'i}os and C. L{\'o}pez and M. E. {\'A}lvarez and J. E. P{\'e}rez and Mabel E. Boh{\'o}rquez},
  journal={BMC Veterinary Research},
  year={2016},
  volume={12}
}
  • J. Carmona, D. L. Ríos, +3 authors Mabel E. Bohórquez
  • Published 2016
  • Chemistry, Medicine
  • BMC Veterinary Research
  • BackgroundPlatelet-rich plasma (PRP) preparations are a common treatment in equine osteoarthritis (OA). However, there are controversies regarding the ideal concentration of platelets and leukocytes in these biological substances necessary to induce an adequate anti-inflammatory and anabolic response in articular cartilage. The aims were to study the influence of leukocyte- and platelet-rich gel (L-PRG) and pure platelet-rich gel (P-PRG) supernatants on the histological changes of cartilage… CONTINUE READING
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