In vitro effects of pentoxifylline on smooth muscle cell migration and blood monocyte production of chemotactic activity for smooth muscle cells: potential therapeutic benefit in the adult respiratory distress syndrome.

@article{Kullmann1993InVE,
  title={In vitro effects of pentoxifylline on smooth muscle cell migration and blood monocyte production of chemotactic activity for smooth muscle cells: potential therapeutic benefit in the adult respiratory distress syndrome.},
  author={A Kullmann and Pascal Vaillant and Volker Muller and Yves Martinet and Nadine Martinet},
  journal={American journal of respiratory cell and molecular biology},
  year={1993},
  volume={8 1},
  pages={83-8}
}
The adult respiratory distress syndrome (ARDS) is a severe lung condition characterized by an acute lung injury leading to a massive intra-alveolar fibrosis with rapid lung failure. ARDS intra-alveolar fibrosis results from the migration of mesenchymal cells (mainly smooth muscle cells [SMC]) into the alveoli through alveolar epithelial basement membrane gaps resulting from the injury. SMC migration is followed by their replication and production of extracellular matrix, which leads to fibrosis… CONTINUE READING

Similar Papers

Loading similar papers…