In vitro effects of Uranium on human fetal germ cells.

  title={In vitro effects of Uranium on human fetal germ cells.},
  author={Ga{\"e}lle Angenard and Vincent Muczynski and Herv{\'e} Coffigny and Clotilde Duquenne and Ren{\'e} Frydman and Ren{\'e} Habert and Gabriel Livera and Virginie Rouiller-Fabre},
  journal={Reproductive toxicology},
  volume={31 4},
Uranium (U) is found in the environment and its use in industrial or military activities has led to concerns about its potential toxicity. The reprotoxicity of this heavy metal has been established in adult animals; however, no studies have examined its effect on human fetal gonads. Using an organ culture system, we investigated the effects of uranyl acetate on human gonads during the first trimester of gestation (7-12 weeks), which is a critical step in the development of a functional… CONTINUE READING
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