In vitro effect of oestradiol on thymidine uptake in pulmonary vascular smooth muscle cell: role of the endothelium.

@article{Farhat1992InVE,
  title={In vitro effect of oestradiol on thymidine uptake in pulmonary vascular smooth muscle cell: role of the endothelium.},
  author={Monique Farhat and Ram{\'o}n G{\'a}lvez Vargas and B Dingaan and Peter W. Ramwell},
  journal={British journal of pharmacology},
  year={1992},
  volume={107 3},
  pages={679-83}
}
1. The effect of different concentrations of oestradiol-17 beta (3-300 nM) on [3H]-thymidine uptake was studied in segments from canine pulmonary artery, and cultures of rat pulmonary vascular smooth muscle cells (VSMC). 2. Incubation with oestradiol-17 beta for 24 h, potentiated in a concentration-dependent manner [3H]-thymidine uptake in VSMC cultures. 3. Oestradiol-17 beta potentiated thymidine uptake by pulmonary arterial segments but only when the endothelium had been removed… CONTINUE READING
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