In vitro differentiation process of human Wharton’s jelly mesenchymal stem cells to male germ cells in the presence of gonadal and non-gonadal conditioned media with retinoic acid

@article{Amidi2015InVD,
  title={In vitro differentiation process of human Wharton’s jelly mesenchymal stem cells to male germ cells in the presence of gonadal and non-gonadal conditioned media with retinoic acid},
  author={Fardin Amidi and Nahid Ataie Nejad and Marziyeh Agha Hoseini and Karim Nayernia and Zohreh Mazaheri and Nazila Yamini and Sara Saeednia},
  journal={In Vitro Cellular \& Developmental Biology - Animal},
  year={2015},
  volume={51},
  pages={1093-1101}
}
Human umbilical Wharton’s jelly-derived mesenchymal stem cells (HWJMSCs) are the best candidate to get plentiful stem cells and differentiate them to germ cells under appropriate conditions to treat infertility. We sought to determine under which conditions HWJMSCs could form male germ cells in vitro. So, HWJMSCs were differentiated to male germ cells under a mixture of bone morphogenetic protein-4 (BMP-4) and testicular and placental culture condition (TCC and PCC) medium followed by retinoic… 
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