In vitro differences between keratinocyte stem cells and transit-amplifying cells of the human hair follicle.

@article{Roh2005InVD,
  title={In vitro differences between keratinocyte stem cells and transit-amplifying cells of the human hair follicle.},
  author={Cecilia Roh and Qingfeng Tao and Christos Demetris Photopoulos and Stephen Lyle},
  journal={The Journal of investigative dermatology},
  year={2005},
  volume={125 6},
  pages={1099-105}
}
Epithelial stem cells within the human hair follicle are critical for hair development, hair cycling, wound healing, and tumorigenesis. We and others have previously shown that the hair follicle bulge area contains keratinocyte stem cells, whereas the hair matrix represents the proliferating and differentiating transit-amplifying (TA) cell compartment. In order to better characterize the phenotypic differences between human keratinocyte stem cells and their daughter TA cells, we compared the in… CONTINUE READING

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