In vitro development of resistance to nystatin by Candida albicans and Torulopsis glabrata.

@article{Nobre1980InVD,
  title={In vitro development of resistance to nystatin by Candida albicans and Torulopsis glabrata.},
  author={Gustavo Nobre and Arturo Pereira and R C{\'o}ias and Jos{\'e} Antonio Cordeiro},
  journal={Journal of general microbiology},
  year={1980},
  volume={118 1},
  pages={263-5}
}
The levels of resistance to nystatin induced in 16 strains of Torulospsis glabrata by a few subcultures in the presence of the drug were high (minimum inhibitory concentrations > 20 000 U ml-1) compared with those obtained in 12 strains of Candida albicans (minimum inhibitory concentrations less than or equal to 2000 U ml-1). The results suggest a high rate of mutation in the first species.