In vitro development of B cells and macrophages from early mouse fetal thymocytes.

@article{Pault1994InVD,
  title={In vitro development of B cells and macrophages from early mouse fetal thymocytes.},
  author={Bruno P{\'e}ault and Ibrahim Khazaal and Irving L Weissman},
  journal={European journal of immunology},
  year={1994},
  volume={24 3},
  pages={781-4}
}
The developmental potentialities of early mouse fetal thymocytes were analyzed by in vitro culturing cell suspensions obtained from 12-15-gestational day thymus in contact with a bone marrow stroma clonal cell line that supports pre-B and myeloid cell differentiation. B cell and macrophage development from fetal thymocytes was observed at all fetal stages tested, but limiting dilution analysis revealed that the frequency of cells forming colonies on bone marrow stroma is the highest in the… CONTINUE READING

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