In vitro deterioration of rhein anthraquinone in cecal content of rats.


The influence of the intestinal microbial reduction of rhein anthraquinone on the formation of deterioration products was studied. Therefore [14C]rhein and [14C]rhein anthrone were mixed with sterilized or non-sterilized cecal mass of rats and incubated for 20 hours at 37 degrees C. Extractions with a methanol-water (50:50) mixture or 4-nitroso-N,N… (More)