In vitro delivery of dexamethasone using hydroxyapatite reservoirs.

@article{Billotte1997InVD,
  title={In vitro delivery of dexamethasone using hydroxyapatite reservoirs.},
  author={W G Billotte and Pramod K. Bajpai},
  journal={Biomedical sciences instrumentation},
  year={1997},
  volume={34},
  pages={13-7}
}
Dexamethasone has been shown to stimulate bone nodule formation in vitro. A hydroxyapatite (HA) reservoir drug release device was designed to release dexamethasone in vitro. Two HA particle sizes (< 38 microns or 63-75 microns) were used to fabricate the reservoirs. Each HA reservoir was loaded with 2 mg of dexamethasone and suspended in 100 ml of 50… CONTINUE READING