In vitro degradation of porous poly(propylene fumarate)/poly(DL-lactic-co-glycolic acid) composite scaffolds.

@article{Hedberg2005InVD,
  title={In vitro degradation of porous poly(propylene fumarate)/poly(DL-lactic-co-glycolic acid) composite scaffolds.},
  author={Elizabeth L Hedberg and Charles K Shih and Jeremy J. Lemoine and Mark Timmer and Michael A. K. Liebschner and John A. Jansen and Antonios G Mikos},
  journal={Biomaterials},
  year={2005},
  volume={26 16},
  pages={3215-25}
}
This study investigated the in vitro degradation of porous poly(propylene fumarate) (PPF-based) composites incorporating microparticles of blends of poly(DL-lactic-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) during a 26-week period in pH 7.4 phosphate-buffered saline at 37 degrees C. Using a fractional factorial design, four formulations of composite scaffolds were fabricated with varying PEG content of the microparticles, microparticle mass fraction of the composite material, and… CONTINUE READING

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