In vitro cytotoxicity of organic pollutants to bluegill sunfish (BF-2) cells.

@article{Babich1987InVC,
  title={In vitro cytotoxicity of organic pollutants to bluegill sunfish (BF-2) cells.},
  author={Harvey Babich and Ellen Borenfreund},
  journal={Environmental research},
  year={1987},
  volume={42 1},
  pages={
          229-37
        }
}
BF-2 cells, an established cell line derived from bluegill sunfish, (Lepomis macrochirus), were exposed to 18 organic toxicants, with cytotoxicity being assayed by the neutral red (NR) technique. Based on the concentration of toxicant that reduced lysosomal uptake of neutral red by 50% (NR50), the rank order of cytotoxicity was methyl mercury greater than pentachlorophenol greater than 2,3,5,6-tetrachlorophenol greater than 2,3,5-trichlorophenol greater than 2,3-dinitrotoluene greater than 2,4… CONTINUE READING

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