In vitro cytotoxic evaluation of some synthesized COX-2 inhibitor derivatives against a panel of human cancer cell lines

@inproceedings{Sadeghialiabadi2013InVC,
  title={In vitro cytotoxic evaluation of some synthesized COX-2 inhibitor derivatives against a panel of human cancer cell lines},
  author={Hojjat Sadeghi-aliabadi and M. Aliasgharluo and Ali Fattahi and Mina Mirian and Mustafa Ghannadian},
  booktitle={Research in pharmaceutical sciences},
  year={2013}
}
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) developed as a selective inhibitor of cyclooxygenase-2 (COX-2) for the treatment of rheumatoid arthritis disease. Recently some other mechanisms have been identified for anti cancer activity of these agents including induction of apoptosis, inhibition of tumor vascularization, stimulation of antitumor immune responses and inhibition of cellular protein synthesis. The cytotoxic effects of four synthesisized analogues of celecoxib (coded… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 24 references

The role of celecoxib in Rad 51 expression and cell survival affected by gefitinib in human non - small

J Chungko, L Hanwang, +3 authors S Tinglin
cell lung cancer cells Lung Cancer • 2009

Similar Papers

Loading similar papers…