In vitro cytotoxic and genotoxic effects of diphenylarsinic acid, a degradation product of chemical warfare agents.

Abstract

Diphenylarsinic acid [DPAs(V)], a degradation product of diphenylcyanoarsine or diphenylchloroarsine, both of which were developed as chemical warfare agents, was investigated in terms of its capacity to induce cytotoxic effects, numerical and structural changes of chromosomes, and abnormalities of centrosome integrity and spindle organizations in… (More)

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