In vitro cytotoxic activity of isolated compounds from Malaysian Calophyllum species

@article{Lim2016InVC,
  title={In vitro cytotoxic activity of isolated compounds from Malaysian Calophyllum species},
  author={Chan Kiang Lim and Subramaniam Hemaroopini and Shu Ying Gan and Siew Mian Loo and Jo Ring Low and Vivien Yi Mian Jong and Hsien Chuen Soo and Chee Onn Leong and Chun Wai Mai and Chin Fei Chee},
  journal={Medicinal Chemistry Research},
  year={2016},
  volume={25},
  pages={1686-1694}
}
Cancer is a leading cause of death worldwide. In our continuing search for new anticancer agents, four Malaysian Calophyllum species, namely C. castaneum, C. teysmannii, C. canum, and C. sclerophyllum, had been phytochemically studied to give compounds 1–12. All the isolated compounds were evaluated for their antiproliferative activity against nasopharyngeal (SUNE1, TW01, CNE1, HK1) and breast (HCC38, MDA-MB-231, MDA-MB-468, SKBR3) cancer cell lines via methyl thiazolyl tetrazolium cell… CONTINUE READING

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