In vitro construction of scaffold-free cylindrical cartilage using cell sheet-based tissue engineering

@article{Tani2009InVC,
  title={In vitro construction of scaffold-free cylindrical cartilage using cell sheet-based tissue engineering},
  author={Gakuto Tani and Noriaki Usui and Masafumi Kamiyama and Takaharu Oue and Masahiro Fukuzawa},
  journal={Pediatric Surgery International},
  year={2009},
  volume={26},
  pages={179-185}
}
Tissue-engineered cartilage may offer a solution for the treatment of serious airway disease. This study developed a novel procedure to fabricate a scaffold-free cylindrical cartilage under in vitro conditions, while also evaluating the effect of a dynamic culture on the engineered construct. Auricular chondrocytes were harvested from New Zealand white rabbits and cultivated under high-density conditions to form a chondrocyte sheet. The sheet was looped around a silicon tube and cultivated for… CONTINUE READING

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