In vitro characterization of a spontaneously immortalized human Müller cell line (MIO-M1).

@article{Limb2002InVC,
  title={In vitro characterization of a spontaneously immortalized human M{\"u}ller cell line (MIO-M1).},
  author={Gloria Astrid Limb and Thomas E. Salt and Peter M. G. Munro and Stephen E Moss and Peng T. Khaw},
  journal={Investigative ophthalmology & visual science},
  year={2002},
  volume={43 3},
  pages={864-9}
}
PURPOSE To characterize a spontaneously immortalized human Müller cell line and to determine whether it retains the characteristics of primary isolated cells without undergoing differentiation in vitro. METHODS An immortalized cell line obtained from human retina was investigated for the expression of known markers of Müller cells, including cellular retinaldehyde binding protein (CRALBP), glutamine synthetase, epidermal growth factor receptor (EGF-R), alpha-smooth muscle actin (alpha-SMA… CONTINUE READING
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