In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia.

@article{Kaspers1997InVC,
  title={In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia.},
  author={Gertjan J L Kaspers and Anjo J. P. Veerman and R. T. Pieters and Christina H van Zantwijk and Lou A. Smets and Elisabeth R. van Wering and Anna van der Does-van den Berg},
  journal={Blood},
  year={1997},
  volume={90 7},
  pages={
          2723-9
        }
}
As an important determinant of the response to chemotherapy, measurements of cellular drug resistance may provide prognostically significant information, which could be useful for optimal risk-group stratification. The objective of this report is to determine the relation between in vitro resistance to 12 drugs, measured with the colorimetric methyl-thiazol-tetrazolium (MTT) assay, and long-term clinical response to chemotherapy in 152 children with newly diagnosed acute lymphoblastic leukemia… CONTINUE READING

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