In-vitro bipolar nano- and microsecond electro-pulse bursts for irreversible electroporation therapies.

@article{Sano2014InvitroBN,
  title={In-vitro bipolar nano- and microsecond electro-pulse bursts for irreversible electroporation therapies.},
  author={Michael B. Sano and Christopher B. Arena and Matthew R. DeWitt and Dieter Saur and Rafael V. Davalos},
  journal={Bioelectrochemistry},
  year={2014},
  volume={100},
  pages={69-79}
}
Under the influence of external electric fields, cells experience a rapid potential buildup across the cell membrane. Above a critical threshold of electric field strength, permanent cell damage can occur, resulting in cell death. Typical investigations of electroporation effects focus on two distinct regimes. The first uses sub-microsecond duration, high field strength pulses while the second uses longer (50 μs+) duration, but lower field strength pulses. Here we investigate the effects of… CONTINUE READING
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