In vitro biological characteristics of human cord blood-derived megakaryocytes.

  title={In vitro biological characteristics of human cord blood-derived megakaryocytes.},
  author={Li Sun and Pamela Vianne C. Tan and Christine H. A. Yap and William Hwang and Liang Piu Koh and Chun Kyu Lim and Swee Eng Aw},
  journal={Annals of the Academy of Medicine, Singapore},
  volume={33 5},
INTRODUCTION Umbilical cord blood (CB) has been used as an alternative source for haematopoietic stem cell transplantation (HSCT) in recent years. However, delayed platelet recovery is frequently associated with CB HSCT. Megakaryocytes (Mk) are the specialised precursors of platelets and they are among the rarest haemopoietic cell types. Despite the rapid expansion of our knowledge of megakaryopoiesis in recent years, many questions, such as the molecular regulatory mechanisms in Mk… CONTINUE READING
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