In vitro binding of purified murine ecotropic retrovirus envelope surface protein to its receptor, MCAT-1.

@article{Davey1997InVB,
  title={In vitro binding of purified murine ecotropic retrovirus envelope surface protein to its receptor, MCAT-1.},
  author={Robert A Davey and Clare Hamson and J. J. Healey and James M Cunningham},
  journal={Journal of virology},
  year={1997},
  volume={71 11},
  pages={
          8096-102
        }
}
An amino-terminal portion of the Friend murine leukemia virus (MLV) envelope surface protein [SU, residues 1 to 236 [SU:(1-236)]] and its receptor, MCAT-1, were each purified from insect cells after expression by using recombinant baculoviruses. Friend SU:(1-236) bound specifically to Xenopus oocytes that expressed MCAT-1 with an affinity (Kd, 55 nM) similar to that of viral SU binding to permissive cells. Direct binding of Friend SU:(1-236) to purified MCAT-1 was observed in detergent and… CONTINUE READING
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Retrovirus envelope domain at 1.7 angstrom resolution.

Nature structural biology • 1996
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A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family.

Proceedings of the National Academy of Sciences of the United States of America • 1994
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