In vitro approach to predict post-translational phosphorylation response to mixtures.

@article{Boyd2013InVA,
  title={In vitro approach to predict post-translational phosphorylation response to mixtures.},
  author={J Wesley Boyd and Julie A. Vrana and Holly Williams},
  journal={Toxicology},
  year={2013},
  volume={313 2-3},
  pages={113-21}
}
While exposure to chemical mixtures is an everyday reality, an understanding of their combined effects, and any potential prediction thereof, is extremely limited. Realistic exposures potentially consist of hundreds to thousands of chemicals per day, but even relatively simple binary mixture interactions can be inherently difficult to predict based upon the lack of temporal and spatial mechanisms for the individual constituents. To this end, we explore the concept of capitalizing on downstream… CONTINUE READING