In vitro antiviral activity of marine sponges collected off Brazilian coast.

@article{Silva2006InVA,
  title={In vitro antiviral activity of marine sponges collected off Brazilian coast.},
  author={A. C. da Silva and J. Kratz and F. M. Farias and A. Henriques and J. Dos Santos and R. Leonel and C. Lerner and B. Mothes and C. R. Barardi and C. Sim{\~o}es},
  journal={Biological & pharmaceutical bulletin},
  year={2006},
  volume={29 1},
  pages={
          135-40
        }
}
This paper describes the in vitro antiviral evaluation of 27 different marine sponges (Porifera) collected off Brazilian coastline in the search for novel drug leads. With these sponges aqueous and organic extracts were prepared and tested for anti-herpetic (HSV-1, KOS strain), anti-adenovirus (human AdV serotype 5) and anti-rotavirus (simian RV SA11) activities. The evaluation of the cytotoxicity and potential antiviral activity of these extracts were performed by using MTT assay. Results were… Expand
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