In vitro antiproliferative activity of docetaxel (Taxotere), paclitaxel (Taxol) and cisplatin against human tumour and normal bone marrow cells.

@article{Braakhuis1994InVA,
  title={In vitro antiproliferative activity of docetaxel (Taxotere), paclitaxel (Taxol) and cisplatin against human tumour and normal bone marrow cells.},
  author={Boudewijn J. M. Braakhuis and Bridget T. Hill and Manfred Dietel and Lloyd R. Kelland and Matti S. Aapro and Wainer Zoli and Peter Lelieveld},
  journal={Anticancer research},
  year={1994},
  volume={14 1A},
  pages={205-8}
}
The in vitro antiproliferative effect of docetaxel (Taxotere), paclitaxel (Taxol) and cisplatin was assessed in a range of human tumour types, including 25 tumour cell lines and 35 primary cultures. Additionally, 12 human normal bone marrow samples were analyzed. Seven laboratories, all members of the EORTC Preclinical Therapeutic Models Group (PTMG), have performed these tests, using their own individual assay procedures. In all comparisons docetaxel and paclitaxel were much more potent than… CONTINUE READING