In vitro antiplasmodial activity of some plants used in Kisii, Kenya against malaria and their chloroquine potentiation effects.

@article{Muregi2003InVA,
  title={In vitro antiplasmodial activity of some plants used in Kisii, Kenya against malaria and their chloroquine potentiation effects.},
  author={Francis W Muregi and Sumesh Chander Chhabra and Eliud Mwaniki Njagi and Caroline Lang'at-Thoruwa and Wilson M. Njue and Alloys S S Orago and Sabah Ahmed Omar and Isaiah Omolo Ndiege},
  journal={Journal of ethnopharmacology},
  year={2003},
  volume={84 2-3},
  pages={
          235-9
        }
}
Fifty-five organic and aqueous extracts of 11 plants used in malaria therapy in Kisii District, Kenya were tested in vitro against chloroquine (CQ)-sensitive and resistant strains of Plasmodium falciparum. Of the plants tested, 73% were active (IC(50) < 100 microg/ml). Three plants, Vernonia lasiopus, Rhamnus prinoides and Ficus sur afforded extracts with IC(50) values ranging less than 30 microg/ml against both CQ-sensitive and resistant strains. Combination of some extracts with CQ against… Expand
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