In vitro antioxidant activity of pravastatin provides vascular protection.

Abstract

The production of reactive oxygen species plays roles during the development of endothelial dysfunction and it represents a significant prognostic factor for evaluating the risk of cardiovascular disease. Although statins target cholesterol biosynthesis, the beneficial effects on cardiovascular disease remain to be fully elucidated. In this work, we… (More)
DOI: 10.1016/j.ejphar.2009.12.037

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