• Corpus ID: 38854584

In vitro antioxidant activity of coumarin compounds by DPPH , Super oxide and nitric oxide free radical scavenging methods

@inproceedings{Patel2011InVA,
  title={In vitro antioxidant activity of coumarin compounds by DPPH , Super oxide and nitric oxide free radical scavenging methods},
  author={S. K. Patel},
  year={2011}
}
Many coumarins and their derivatives exert anti-coagulant, anti-tumor, anti-viral, antiinflammatory and antioxidant effects, as well as anti-microbial and enzyme inhibition properties. The different substituents in the coumarin nucleus strongly influence the biological activity of the resulting derivatives. Although some coumarins have been already characterized to evoke a particular biological activity, the challenge would be the design and synthesis of new derivatives with high specific… 

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References

SHOWING 1-10 OF 29 REFERENCES

EVALUATION OF ANTIOXIDANT, ANTI-INFLAMMATORY AND LIPOXYGENASE INHIBITORY ACTIVITIES OF THE PRENYLATED COUMARIN UMBELLIPRENIN

TLDR
The observed inhibition of lipoxygenase may be a plausible mechanism for the potent cancer chemopreventive activity of umbelliprenin and may pose this compound as a valuable agent for the treatment of inflammatory diseases.

Natural compounds, fraxin and chemicals structurally related to fraxin protect cells from oxidative stress

TLDR
Fraxin recovered viability of HUVECs damaged by H2O2- treatment and reduced the lipid peroxidation and the internal reactive oxygen species level elevated by H 2O2 treatment and reverse transcription-PCR revealed that fraxin upregulated antiapoptotic genes and tumor suppressor gene.

SIDA VERONICAEFOLIA AS A SOURCE OF NATURAL ANTIOXIDANT

Antioxidants play a major role in the management of diseases which are associated with oxidative stresses caused by excess free radicals and other reactive oxygen species. Antioxidant phytochemicals

Antioxidant and Free Radical Scavenging Properties of Developed Mono- and Polyherbal Formulations

The antioxidant properties of developed mono and polyherbal tablet formulations viz. Withatab, Asparatab, Centab and Ascenwit that probably involve free radical mechanisms, were evaluated by the

ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITY

Extracts of 4 medicinal and aromatic plants were investigated for their antioxidant potency employing six various established in vitro system: H. officinalis L. var. angustifolius aerial parts, C.

Evaluation of free radical scavenging activity of Butea monosperma Lam.

TLDR
HPTLC fingerprint profile of the ethyl acetate and butanol fractions were developed which would serve as reference standard for quality control of the extracts.

The contribution of the pyrogallol moiety to the superoxide radical scavenging activity of flavonoids.

TLDR
It can be concluded that the pyrogallol moiety is an active component of flavonoids for displaying high O2-* scavenging activity.

Antioxidant activities of methanol extract of Sambucus ebulus L. flower.

TLDR
It was found that antioxidant activity of methanol extract of Sambucus ebulus L. flower was dose dependent i.e., activity was increased with the increase of their concentrations.

Kinetics and Mechanisms of Antioxidant Activity using the DPPH.Free Radical Method

Abstract The reaction mechanisms of three antioxidants are proposed in order to explain experimental results obtained from a kinetic study using the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH .

Nitric oxide and peroxynitrite in health and disease.

TLDR
Current evidence indicates that most of the cytotoxicity attributed to NO is rather due to peroxynitrite, produced from the diffusion-controlled reaction between NO and another free radical, the superoxide anion, which is presented in detail in this review.