In vitro antimicrobial efficacy of a silver alginate dressing on burn wound isolates.

@article{Thomas2011InVA,
  title={In vitro antimicrobial efficacy of a silver alginate dressing on burn wound isolates.},
  author={J. G. Thomas and Will Slone and Sara Linton and Tyler Okel and Linda Corum and Steven L. Percival},
  journal={Journal of wound care},
  year={2011},
  volume={20 3},
  pages={
          124,126-8
        }
}
OBJECTIVE To test the antimicrobial effectiveness of a silver alginate dressing on opportunistic pathogens, namely meticillin-sensitive Staphylococcus aureus (MSSA) and meticillin-resistant Staphylococcus aureus (MRSA), Klebsiella spp., Enterococcus faecalis, Enterococcus faecium, Pseudomonas aeruginosa, Escherichia coli, Enterobacter sakazakii, Enterobacter cloacae, Serratia marcescens, Chryseobacterium indologenes, Proteus vulgaris and Acinetobacter baumannii. METHOD In total, 40… 
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The efficacy of silver dressings and antibiotics on MRSA and MSSA isolated from burn patients
TLDR
It was evident from the data generated that both pH and the bacterial phenotypic state are factors that induce changes that affect both antimicrobial performance and bacterial susceptibility, and showed that the effect of pH and bacterial phenotypesic state must be considered when the antimicrobial activity of silver wound dressings is being investigated.
The antimicrobial efficacy of silver on antibiotic‐resistant bacteria isolated from burn wounds
TLDR
All forty‐nine antibiotic‐resistant bacteria isolated from burn wounds showed susceptibility to the antimicrobial activity of both silver containing wound dressings over all pH ranges, indicating that the performance of both dressings apparently increased when pH became more acidic.
The visualisation and speed of kill of wound isolates on a silver alginate dressing
TLDR
The data highlights the rapid speed of kill and antimicrobial suitability of this RESTORE silver alginate dressing on wound isolates and highlights its overwhelming ability to manage a microbial wound bioburden in the management of infected wounds.
Antibacterial properties and reduction of MRSA biofilm with a dressing combining polyabsorbent fibres and a silver matrix.
TLDR
These in vitro experiments demonstrated that silver polyabsorbent dressing was able to strongly reduce the biofilm of MRSA.
Silver and Alginates: Role in Wound Healing and Biofilm Control.
TLDR
It is very important that inventors of antimicrobial wound dressings ensure efficacy against both planktonic and sessile microorganisms, within the in vitro and in vivo environments.
Antimicrobial Efficacy and Synergy of Metal Ions against Enterococcus faecium, Klebsiella pneumoniae and Acinetobacter baumannii in Planktonic and Biofilm Phenotypes
TLDR
Overall, platinum, palladium and gold metal ion solutions in individual use or combination demonstrated the greatest antimicrobial efficacies against planktonic or biofilm bacteria.
New Antibacterial Paper Made of Silver Phosphate Cellulose Fibers: A Preliminary Study on the Elimination of Staphylococcus aureus Involved in Diabetic Foot Ulceration
TLDR
The efficiency of SPCF paper is shown to eliminate Staphylococcus aureus when compared with other common commercial products and could have an industrial potential in wound care.
Restoring balance: biofilms and wound dressings.
TLDR
The aim of the paper is to review the ideal characteristics of wound dressings, in conjunction with antimicrobials, that are considered a fundamental part of an antibiofilm strategy and growing requirement for enhanced wound healing.
Alginate films functionalized with silver sulfadiazine-loaded [Mg-Al] layered double hydroxide as antimicrobial wound dressing.
Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing
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TLDR
Analysis of the efficacy of silver-containing dressings on the silver-resistant strains of Enterobacter cloacae showed that, despite evidence of genetic resistance to silver, all strains were killed following a maximum of 48 hours of exposure to the dressings.
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TLDR
Contreet-H has broadly similar antimicrobial activity to Acticoat, but has a slower onset of action, and Actisorb Silver 220 appears to offer less prospect of killing bacteria within the wound itself, but the dressing is capable of removing micro-organisms from wound exudate and sequestering them until they are inactivated by the silver within the charcoal fibres.
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TLDR
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