In vitro antigenotoxicity of Ulva rigida C. Agardh (Chlorophyceae) extract against induction of chromosome aberration, sister chromatid exchange and micronuclei by mutagenic agent MMC.

@article{Celikler2008InVA,
  title={In vitro antigenotoxicity of Ulva rigida C. Agardh (Chlorophyceae) extract against induction of chromosome aberration, sister chromatid exchange and micronuclei by mutagenic agent MMC.},
  author={Serap Celikler and Gamze Yildiz and Ozgur Vatan and Rahmi Bilaloğlu},
  journal={Biomedical and environmental sciences : BES},
  year={2008},
  volume={21 6},
  pages={
          492-8
        }
}
OBJECTIVE To determine the in vitro possible clastogenic and cytotoxic activities of Ulva rigida crude extracts (URE), and identify their antigenotoxic and protective effects on chemotherapeutic agent mitomycine-C (MMC). METHODS Anti-clastogenic and anti-genotoxic activities of Ulva rigida crude extracts (URE) were studied using chromosome aberration (CA), sister chromatid exchange (SCE), and micronuclei (MN) tests in human lymphocytes cultured in vitro. RESULTS The chromosome aberration… CONTINUE READING

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