In vitro antifungal activity of the flavonoid baicalein against Candida species.

@article{Serpa2012InVA,
  title={In vitro antifungal activity of the flavonoid baicalein against Candida species.},
  author={Rosana Serpa and Emanuele J{\'u}lio Galv{\~a}o de França and Luciana Furlaneto-Maia and C{\'e}lia Guadalupe Tardeli de Jesus Andrade and Andr{\'e}a Diniz and M{\'a}rcia C Furlaneto},
  journal={Journal of medical microbiology},
  year={2012},
  volume={61 Pt 12},
  pages={1704-8}
}
The aim of the present study was to evaluate the in vitro activity of baicalein, the flavone constituent of Scutellaria baicalensis, and synergism of the combination of baicalein and fluconazole against Candida albicans, Candida tropicalis and Candida parapsilosis. The MIC(50) (lowest concentration at which there was 50 % inhibition of growth) of baicalein alone against six Candida strains ranged from 13 to 104 µg ml(-1). For the three species tested, exposure to baicalein at the MIC(50… CONTINUE READING
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