In vitro antibacterial properties of BRL 36650, a novel 6 alpha-substituted penicillin

  title={In vitro antibacterial properties of BRL 36650, a novel 6 alpha-substituted penicillin},
  author={Michael J. Basker and R. A. Edmondson and Sarah J. Knott and Roger J. Ponsford and Brian Slocombe and Scott White},
  journal={Antimicrobial Agents and Chemotherapy},
  pages={734 - 740}
BRL 36650 is a new type of penicillin in which a formamido group has been introduced into the 6 alpha-position of the nucleus. The compound is highly active against aerobic gram-negative bacteria and is stable to a wide range of beta-lactamases produced by these organisms. Against members of the family Enterobacteriaceae, BRL 36650 was considerably more active than piperacillin, particularly against beta-lactamase-producing strains, and showed a similar level of activity to moxalactam… 
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    Reviews of infectious diseases
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