In vitro antibacterial activity of faeriefungin, a new broad-spectrum polyene macrolide antibiotic.

@article{Mulks1990InVA,
  title={In vitro antibacterial activity of faeriefungin, a new broad-spectrum polyene macrolide antibiotic.},
  author={Martha H. Mulks and Muraleedharan G Nair and Alan R. Putnam},
  journal={Antimicrobial agents and chemotherapy},
  year={1990},
  volume={34 9},
  pages={1762-5}
}
The in vitro activity of faeriefungin, a new pentaene macrolide lactone antibiotic produced by Streptomyces griseus var. autotrophicus, against 263 clinical bacterial isolates was examined. In contrast to the related fungicidal antibiotics nystatin and amphotericin B, which show no activity against bacteria, faeriefungin showed bactericidal activity against all species of gram-positive bacteria examined. MICs for these species ranged from 8 to 64 micrograms/ml, and the MIC for 90% of the… CONTINUE READING

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