In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica.

  title={In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica.},
  author={A. Shukla and A. M. Rasik and G. Jain and R. Shankar and D. K. Kulshrestha and B. N. Dhawan},
  journal={Journal of ethnopharmacology},
  volume={65 1},
  • A. Shukla, A. M. Rasik, +3 authors B. N. Dhawan
  • Published 1999
  • Medicine
  • Journal of ethnopharmacology
  • The activity of asiaticoside, isolated from Centella asiatica, has been studied in normal as well as delayed-type wound healing. [...] Key Result In guinea pig punch wounds topical applications of 0.2% solution of asiaticoside produced 56% increase in hydroxyproline, 57% increase in tensile strength, increased collagen content and better epithelisation.Expand Abstract
    Nutritional support for wound healing.
    • 396
    • PDF
    Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all
    • 258
    • PDF


    Publications referenced by this paper.
    Protein measurement with the Folin phenol reagent.
    • 272,088
    The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.
    • 3,367
    • Highly Influential
    Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica.
    • 139
    • Highly Influential
    Wound therapy: growth factors as agents to promote healing.
    • 80
    Induction of angiogenesis by bovine brain derived class 1 heparin-binding growth factor.
    • 161
    Effect of Asiaticoside on Wound Healing in the Rat
    • 41