In vitro and in vivo toxicological study of the Pterodon pubescens seed oil.

@article{Sabino1999InVA,
  title={In vitro and in vivo toxicological study of the Pterodon pubescens seed oil.},
  author={K{\'a}tia C Carvalho Sabino and Carlos Roberto Machado Gayer and Luiz Carlos Aguiar Vaz and La{\'e}lcio Lins Ramos Santos and Israel Felzenszwalb and Marsen Garcia Pinto Coelho},
  journal={Toxicology letters},
  year={1999},
  volume={108 1},
  pages={27-35}
}
The oil of Pterodon pubescens seeds (PpSO) is known for its cercaricidal and anti-inflammatory effects. Its anti-rheumatic activity was recently reported using mice with collagen II-induced arthritis treated with a hydroalcoholic extract of PpSO, mimicking the wine infusion used in popular medicine. In the present study, PpSO was tested for acute toxicity, mutagenic activity and cytotoxicity for human peripheral blood mononuclear cells (PBMNC). PpSO was obtained after seed extraction with 100… CONTINUE READING
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