In vitro and in vivo study of the clastogenicity of the flavone cirsitakaoside extracted from Scoparia dulcis L. (Scrophulariaceae).

@article{PereiraMartins1998InVA,
  title={In vitro and in vivo study of the clastogenicity of the flavone cirsitakaoside extracted from Scoparia dulcis L. (Scrophulariaceae).},
  author={S R Pereira-Martins and Catarina Satie Takahashi and Denise Crispim Tavares and Luce Maria Brand{\~a}o Torres},
  journal={Teratogenesis, carcinogenesis, and mutagenesis},
  year={1998},
  volume={18 6},
  pages={293-302}
}
The mutagenic effect of the flavone cirsitakaoside extracted from the medicinal herb Scoparia dulcis was evaluated in vitro by using human peripheral blood cultures treated with doses of 5, 10, and 15 microg of the flavone/ml culture medium for 48 h. The compound proved to be mutagenic at the highest concentration tested (15 microg/ml). Furthermore, the… CONTINUE READING