In vitro and in vivo study of the application of volvox spheres to co-culture vehicles in liver tissue engineering.


Volvox sphere is a biomimetic concept of a natural Volvox, wherein a large outer sphere contains smaller inner spheres, which can encapsulate cells and provide a double-layer three-dimensional environment for culturing cells. This study simultaneously encapsulated rat mesenchymal stem cells (MSCs) and AML12 hepatocytes in volvox spheres and extensively… (More)
DOI: 10.1016/j.actbio.2017.09.028


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