In-vitro and in-vivo studies of the diclofenac sodium controlled-release matrix tablets.

Abstract

Controlled release matrix tablets for diclofenac sodium were developed in this study. Five matrix-tablet formulations were prepared by granulating two viscosity grades of HPMC (hydroxylpropylmethylcellulose) in varying ratios with water in the planetary mixer. The in-vitro dissolution tests indicate that all five matrix formulations prolong the release of… (More)

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Cite this paper

@article{Liu1995InvitroAI, title={In-vitro and in-vivo studies of the diclofenac sodium controlled-release matrix tablets.}, author={C. H. Liu and Y. H. Kao and S. C. Chen and Theodore D. Sokoloski and Ming-Jen Sheu}, journal={The Journal of pharmacy and pharmacology}, year={1995}, volume={47 5}, pages={360-4} }