In vitro and in vivo studies of iron delivery by human monoferric transferrins.

Abstract

According to the Fletcher-Huehns hypothesis there exists a functional difference between the two iron-binding sites of transferrin. In this study we present the results of an evaluation of this hypothesis in vitro and in vivo with human pure monoferric transferrins obtained by preparative isoelectric focusing in granulated gels. The uptake of iron from… (More)

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Cite this paper

@article{Heul1984InVA, title={In vitro and in vivo studies of iron delivery by human monoferric transferrins.}, author={Cees van der Heul and Martin J. Kroos and W L van Noort and H G van Eijk}, journal={British journal of haematology}, year={1984}, volume={56 4}, pages={571-80} }