In vitro and in vivo studies of RNA recognition by Rna15

@inproceedings{Robertson2014InVA,
  title={In vitro and in vivo studies of RNA recognition by Rna15},
  author={Laura Elizabeth Robertson},
  year={2014}
}
For successful gene expression in eukaryotes, mRNA transcripts are processed in the 5’ and 3’ untranslated regions (UTRs) and non-coding mRNA is spliced out. These processes are crucial in determining the fate of the mRNA transcript. Rna14 and Rna15 are subunits of Cleavage factor 1A (CF1A) and required for 3’ end processing in S. cerevisiae. Structural and biophysical data have determined a number of residues within the RNA recognition motif (RRM) of Rna15 that interact directly with RNA… CONTINUE READING

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