In vitro and in vivo osteogenic potential of bioactive glass-PVA hybrid scaffolds colonized by mesenchymal stem cells.

@article{Gomide2012InVA,
  title={In vitro and in vivo osteogenic potential of bioactive glass-PVA hybrid scaffolds colonized by mesenchymal stem cells.},
  author={Viviane Silva Gomide and Alessandra Arcoverde Cavalcanti Zonari and Nat{\'a}lia de Melo Ocarino and Alfredo de Miranda G{\'o}es and Rog{\'e}ria Serakides and Marivalda de Magalh{\~a}es Pereira},
  journal={Biomedical materials},
  year={2012},
  volume={7 1},
  pages={015004}
}
Bioactive glass/polymer composites are promising materials for bone tissue engineering. The present research group has developed porous hybrid scaffolds comprised of 50% polyvinyl alcohol/50% bioactive glass with a 70%SiO(2)-30%CaO composition. Prior studies have also shown the adequate structural and mechanical behavior of these scaffolds. As such, the present study investigates the in vitro and in vivo osteogenic potential of the scaffold, using mesenchymal stem cells (MSC) from the bone… CONTINUE READING