In vitro and in vivo interactions of aluminum on NTPDase and AChE activities in lymphocytes of rats.

@article{Kaizer2010InVA,
  title={In vitro and in vivo interactions of aluminum on NTPDase and AChE activities in lymphocytes of rats.},
  author={Rosilene Rodrigues Kaizer and Jessi{\'e} M Gutierres and Roberta Schmatz and Roselia M Spanevello and Vera M Morsch and Maria Rosa Schetinger and Jo{\~a}o B. T. Rocha},
  journal={Cellular immunology},
  year={2010},
  volume={265 2},
  pages={
          133-8
        }
}
Al adjuvants are used in vaccines to increase the immune response. NTPDase and AChE play a pivotal role and act in the regulation of the immune system. The effect of Al exposure in vitro and in vivo on NTPDase and AChE activities in the lymphocytes of rats was determined. In vitro, ATP hydrolysis was decreased by 20.4% and 17.3% and ADP hydrolysis was decreased by 36.5% and 34.8%, in groups D and E, respectively, when compared to the control. AChE activity was increased by 157.3%, 152.5%, 74.7… CONTINUE READING

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