In vitro and in vivo induction of nitric oxide by murine macrophages stimulated with Bordetella pertussis.

@article{Torre1996InVA,
  title={In vitro and in vivo induction of nitric oxide by murine macrophages stimulated with Bordetella pertussis.},
  author={Donato Torre and Giulio Ferrario and G. Bonetta and Lorenza Perversi and Filippo Speranza},
  journal={FEMS immunology and medical microbiology},
  year={1996},
  volume={13 2},
  pages={95-9}
}
Nitric oxide (NO) exhibits potent antimicrobial activity in vitro. The function of NO in host defenses in vivo, however, is presently unclear. Experiments were undertaken to determine the production of NO in vitro from murine peritoneal and alveolar macrophages, and murine macrophage cell line (J774A.1) stimulated with Bordetella pertussis or pertussis… CONTINUE READING