In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides.

@article{Bagchi1995InVA,
  title={In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides.},
  author={Debasis Bagchi and Manashi Bagchi and Ezdihar A Hassoun and Sidney J Stohs},
  journal={Toxicology},
  year={1995},
  volume={104 1-3},
  pages={
          129-40
        }
}
Reactive oxygen species may be involved in the toxicity of various pesticides and we have, therefore, examined the in vivo effects of structurally dissimilar polyhalogenated cyclic hydrocarbons (PCH), such as endrin and chlordane, chlorinated acetamide herbicides (CAH), such as alachlor, and organophosphate pesticides (OPS), such as chlorpyrifos and fenthion, on the production of hepatic and brain lipid peroxidation and DNA-single strand breaks (SSB), two indices of oxidative stress and… CONTINUE READING
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