In vitro and in vivo expression of inducible nitric oxide synthase during experimental endotoxemia: involvement of other cytokines.

Abstract

In this study, we investigated the expression of genes for inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNF-alpha), interleukin 1 beta (IL-1 beta), interleukin 6 (IL-6) of Kupffer cells in the presence of lipopolysaccharide (LPS), and the tissue expression of iNOS in a rat liver after LPS injection at various time intervals. The… (More)

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@article{Aono1997InVA, title={In vitro and in vivo expression of inducible nitric oxide synthase during experimental endotoxemia: involvement of other cytokines.}, author={Keiya Aono and Kazumasa Isobe and Kenta Kiuchi and Z. H. Fan and M. Ito and Akira Takeuchi and Motohiko Miyachi and Izumi Nakashima and Yoshifumi Nimura}, journal={Journal of cellular biochemistry}, year={1997}, volume={65 3}, pages={349-58} }