In vitro and in vivo evidence for differences in the protease activity of two arabis mosaic nepovirus isolates and their impact on the infectivity of chimeric cDNA clones.

@article{Wetzel2013InVA,
  title={In vitro and in vivo evidence for differences in the protease activity of two arabis mosaic nepovirus isolates and their impact on the infectivity of chimeric cDNA clones.},
  author={Thierry Wetzel and Joan Chisholm and Laurence Dupuis-Maguiraga and Alexandra Bassler and H{\'e}l{\`e}ne Sanfaçon},
  journal={Virology},
  year={2013},
  volume={446 1-2},
  pages={102-11}
}
Regulated processing of nepovirus polyproteins allows the release of mature proteins and intermediate polyproteins. Infectious cDNA clones of the mild NW isolate of arabis mosaic virus (ArMV) and chimeric clones incorporating RNA1 segments of Lv, a severe isolate, were generated. Clones containing the Lv X2-NTB cleavage site were not infectious unless the… CONTINUE READING