In vitro and in vivo evaluation of the indoloquinone EO-9 (NSC 382 459) against human small cell carcinoma of the lung.

Abstract

As the indoloquinone EO-9 has previously shown activity in several tumor model systems it was evaluated against four human small cell lung cancer cell lines by the clonogenic assay. In two cell lines (Nyh and Tol), exponential dose-response curves were achieved with both 1 h and continuous exposure, whereas no cell kill was obtained in the other two cell… (More)

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@article{Roed1989InVA, title={In vitro and in vivo evaluation of the indoloquinone EO-9 (NSC 382 459) against human small cell carcinoma of the lung.}, author={Hanne Roed and Kristian Aabo and Lars Lindhardt Vindel\ov and Mogens Spang-Thomsen and Inger Johanne Christensen and H. H. Hansen}, journal={European journal of cancer & clinical oncology}, year={1989}, volume={25 8}, pages={1197-201} }