In vitro and in vivo evaluation of staphylococcal superantigen peptide antagonists.

@article{Rajagopalan2004InVA,
  title={In vitro and in vivo evaluation of staphylococcal superantigen peptide antagonists.},
  author={Govindarajan Rajagopalan and Moon Moon Sen and Chella S. David},
  journal={Infection and immunity},
  year={2004},
  volume={72 11},
  pages={6733-7}
}
Superantigen peptide antagonists failed to block T-cell activation and cytokine production as well as toxic shock induced by staphylococcal enterotoxin B (SEB) in HLA class II transgenic mice. They also failed to inhibit the binding of SEB to HLA class II molecules as well as activation of human T lymphocytes in vitro. 

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